Sermorelin is a prescription peptide that sends the signal again — so your own pituitary releases growth hormone while you sleep. No synthetic HGH. No clinic visits.
From $199/mo · HSA/FSA eligible · Cancel anytime
THE PROBLEM
Most of your growth hormone is released in pulses during deep sleep. With age those pulses shrink. You don't notice it on a lab report first. You notice it in the mirror and in the morning.
You sleep, but you don't recover. Shallow nights, heavy mornings, coffee by 7.
The same training that built you at 28 now just breaks you down.
Muscle gets harder to keep, fat gets easier to gain — no matter how disciplined you are.
THE MECHANISM
Sermorelin is a GHRH analog — the first 29 amino acids of the signal your hypothalamus already sends. Your body stays in the loop, and its own feedback controls stay intact.
A small under-the-skin injection with an insulin-size needle, as your provider directs.
Sermorelin binds GHRH receptors and prompts a natural growth-hormone pulse.
Growth hormone drives IGF-1 production in the liver — the signal for repair and protein synthesis.
Dosing is adjusted from your check-ins and, where needed, your labs.
WHAT TO EXPECT
WEEKS 2–6
The first change many people report is how they wake up.
MONTHS 2–3
Less time sore between sessions, more capacity to train.
MONTHS 3–6
Changes in lean mass and fat build slowly, alongside training and diet.
Typical timeline. Individual results vary and are not guaranteed.
THE SMARTER ROUTE
| Nightshift Sermorelin | Synthetic HGH | Doing nothing | |
|---|---|---|---|
| How it works | Prompts your own pituitary | Replaces GH from outside | Decline continues |
| Natural feedback loop | Stays intact | Can be suppressed | — |
| Access | Online provider visit | Tightly restricted | — |
| Monthly cost | From $199 | $500–$1,500+ | $0 — and you feel it |
ON A GLP-1?
Fast weight loss can take lean mass with it. Many people on semaglutide or tirzepatide ask about adding sermorelin to support recovery and body composition. Your provider reviews your full medication list and decides whether it fits.
Check if I qualify →PRICING
Provider visit, prescription, medication, supplies and shipping. If you're not approved, you're not charged.
Enough time to see body-composition changes. Billed [TERMS].
Choose 3-monthHOW IT WORKS
Tell us about your health, goals and current medications.
A licensed provider in your state decides if sermorelin is right for you.
Your prescription ships in [X] business days, with ongoing support.
PATIENT REVIEWS
FAQ
A synthetic version of the active part of growth hormone–releasing hormone (GHRH). It prompts your pituitary to release its own growth hormone rather than supplying hormone directly.
Compounded sermorelin is not an FDA-approved finished drug. It is prepared by a licensed US 503A pharmacy for you individually, based on a valid prescription.
A small subcutaneous injection, usually at bedtime. Your provider sets the dose and schedule and walks you through it.
The most common are injection-site redness or swelling, flushing, headache and dizziness. It isn't right for everyone — your provider screens for conditions where it shouldn't be used.
Your provider reviews everything you take and decides. Tell them about every medication during your assessment.
[STATES SERVED — confirm with your telehealth partner]
[YOUR CANCELLATION + REFUND POLICY]
From $199/mo — and $100 off your first month. Not approved? Not charged.
Start my assessment →